Pondelok 7 september
Arthur Ashe Stadium
R4
Williams S [3]
d.
Sakkari M [15]
6/3, 6/76, 6/3
R4
Thiem D [2]
d.
Auger-Aliassime F [15]
7/64, 6/1, 6/1
R4
Medvedev D [3]
d.
Tiafoe F
6/4, 6/1, 6/0
R4
Mertens E [16]
d.
Kenin S [2]
6/3, 6/3
Louis Armstrong Stadium
R4
De Minaur A [21]
d.
Pospisil V
7/66, 6/3, 6/2
R4
Pironkova T
d.
Cornet A
6/4, 6/75, 6/3
R4
Rublev A [10]
d.
Berrettini M [6]
4/6, 6/3, 6/3, 6/3
R4
Azarenka V
d.
Muchova K [20]
5/7, 6/1, 6/4
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Top seeds